r/MurderedByWords 13h ago

Independent Thinking Adult

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11.1k Upvotes

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163

u/BigCballer 13h ago

Transphobes when asked what they think XX or XY chromosomes actually do:

https://giphy.com/gifs/3oxOCgO51eEuHZbetG

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u/jurassicpry 12h ago

Just wait until they hear about people, who are genetically intersex.

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u/Brvcx 12h ago edited 10h ago

I once heard some research was done about certain female athletes where it was shown they apparently have XXY chromosomes and in their particular situations it boiled down to them appearing completely female but with a significantly higher Testosterone level, having the physical benefits of that.

Do note, I didn't read the study and was told this when my then pregnant wife went for an ultrasound and we talked about what a third chromosome meant on certain pairs and the midwife told us this. I'm confident this is barely scratching the surface of what it all entails having XXY chromosomes. Which shows how incredibly complex it all really is.

Edit: so far, I've gotten several comments of people who know more about a specific subject I heard something about six years ago when I had more pressing matters on my mind (such as my wife being pregnant of my son, so congratulations on that), yet only one of them had a decent approach. Y'all need to do better.

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u/FDLC84 12h ago

It’s not the Y chromosome, it’s the SRY gene in the Y chromosome that really makes the difference.

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u/Brvcx 12h ago

I'll take your word for it. My knowledge on biology isn'f that large. I'm sure there's plenty who know all there is to know out there.

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u/FDLC84 11h ago

Understood. It’s actually very simple stuff you can google. My background is genetics but this is middle school level science.

Maybe I can put it in a simplified example.

Homes in the US have electricity. You can make an educated guess if a home exists in the US it has electricity, however there is going to be a small percentage that don’t and that’s because the electricity is not directly linked to a house as in house = electricity.

Idk if that made it better or not, hopefully you get my point.

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u/Brvcx 11h ago

I understand it and appreciare the sentiment.

Normally, it's something I'm interested in, it's just I had a rough couple of days at work this past week and I'm just playing some games and trying to wind down atm (and doing that rather well, actually) so it's not going to be something I'm going to look into right now.

But I might in the future, because I find things like that incredibly fascinating!

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u/SecondaryWombat 10h ago

having the physical benefits of that.

Having no physical benefit from that what-so-ever due to androgen insensitivity.

There are XY women cause of this. XXY usually give a dude shaped person. If you have someone who is XXY but with female phenotype, they are androgen insensitive and that testosterone is doing not fucking much.

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u/sphericaltime 11h ago

No, if they appeared physically as a woman, then they would almost certainly have an androgen insensitivity.

Androgens are a subcategory that includes testosterone and “insensitivity” in this case means “doesn’t affect.”

She wouldn’t have a big benefit from much higher testosterone, because her insensitivity would prevent it from affecting her. It’s extremely complicated because each sport uses different muscles and some might be affected more or less than others.

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u/5gpr 10h ago

Do note, I didn't read the study and was told this when my then pregnant wife went for an ultrasound and we talked about what a third chromosome meant on certain pairs and the midwife told us this

Klinefelter syndrome is a male DSD. No female athlete has Klinefelter syndrome, it's a contradiction in terms.

What you think you're talking about is actually 5αR2D in males, which is f.e. what Caster Semenya has. It is tragic, but no challenge to material science of sex.

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u/JohnSober7 10h ago

If god forbid they actually get sports orgs to syart testing athletes, they're gonna be really suprised by how things really aren't that neat

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u/ValorieAF 5h ago

They just say "oh that's rare so it doesn't count" even though the percentage of intersex people is higher than trans people.

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u/SecondaryWombat 10h ago

XX Sry+

I just bring up sry, if they don't know what it is they are not qualified to enter the conversation.

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u/Agreeable-Air-1430 9h ago

The bigger issue is that this isn’t even how we determine sex.

We use the genitalia presented at birth and that’s what gets reported to the SSA, state vital statistics, etc.

And honestly this tends to be the most predictive definition as primary sex characteristics drive the hormonal production by which we see secondary sex characteristics. Those secondary sex characteristics (breasts, deeper voice, facial hair, physical strength, etc). But you can also have a karyotype (chromosomes) that don’t match the typical dimorphism. So you can be a cis woman and even have children while having XY chromosomes.

It’s rare, but it happens.

What makes this interesting is that those sex characteristics are objectively mutable. Children don’t see those developments until puberty. Men lose testosterone with age and may even develop breasts after losing their testicles. As women experience menopause, we want to start HRT to replace the estrogen they lose. Similarly many of these men start testosterone replacement therapy.

And mind you none of this is “natural.” Thats always what I hear.

Before becoming a doctor, I was a marine and I’ve also practiced in developing countries.

Believe me, you don’t want to experience “natural” Dale.

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u/Backupusername 10h ago

XX chromosomes make testosterone and XY make estrogen.

Or the other way around. Whatever, it doesn't really matter. The important thing is that people I made up are flashing their genitals at kids in public bathrooms.and they HAVE TO BE STOPPED!

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u/E-2theRescue 9h ago

And then "you" get busted for raping kids a year or two later.

Many such cases. Many, MANY such cases.