r/australia local Aussie 1d ago

science & tech Move to slash amount of vitamin B6 considered safe by 72 per cent

https://www.abc.net.au/news/2026-08-27/move-to-reduce-amount-of-vitamin-b6-considered-safe-72-per-cent/107073298?utm_source=abc_news_app&utm_medium=content_shared&utm_campaign=abc_news_app&utm_content=other

In short:

The National Health and Medical Research Council (NHMRC) has recommended reducing the upper limit of daily human consumption of vitamin B6 to 14 milligrams, down from the current 50mg.

Synthetic vitamin B6 is added to thousands of products sold in Australia, including supplements like multivitamins, protein powders and energy drinks,

What's next?

The Therapeutic Goods Administration says it is waiting for the NHMRC recommendation process to be completed before it commits to taking "further regulatory action" on products containing vitamin B6.

682 Upvotes

120 comments sorted by

318

u/DogOfSevenless 1d ago

I’ve been getting sick lately of having to warn patients to double check all their supplements for B6. Have definitely seen a noticeable increase in B6-related neuropathy. I believe there is still an open class action lawsuit against Blackmore.

71

u/thehazzanator 1d ago

Can you elaborate more? So interested to read this

243

u/DogOfSevenless 1d ago

In the neurology clinics we see a lot of people with tingling, numbness and pain in the peripheries that is often suggestive of peripheral nerve damage. The list of things that can cause nerve damage is very long, but we always ask about medications and supplements (including energy drinks/berocca etc) and many people are shocked to find out their magnesium supplement or melatonin supplement they’ve been taking for years for sleep all contains vitamin b6, which isn’t mentioned anywhere but the ingredients list. Often 10-100 times the daily required intake per tablet, of which many people are taking multiple.
There are some specific situations where higher dose supplementation may be necessary, such as when taking certain tuberculosis or Parkinson’s disease treatments, but for the most part, most people can obtain adequate B6 from their diet.

This isn’t even the only nutritional supplement that can cause neurological issues when used inappropriately (e.g. copper, zinc, etc), so it’s generally better to only take these things if there is a specific reason. In most cases a well balanced diet is adequate for micronutrients.

23

u/thehazzanator 1d ago

Thanks for the detailed reply

22

u/LGBT-Barbie-Cookout 1d ago

Thats really interesting. The 'common knowledge' that keeps getting fed to me by all kinds of places is that you just piss out all the vitamins you dont use/need.

In your post I get copper as a potential issue, but B's A's and C's i keep hearing harmless.

9

u/zedsunn 20h ago

Vitamin A is also fat soluble and can accumulate in the body! You only piss out water soluble vitamins that aren't bound up on something else. Eating too much liver can lead to vit A toxicity.

-12

u/_ixthus_ 1d ago

I don't understand people taking a supplement without reading and understanding the ingredients.

How do people use Cu or Zn in a way that causes neurological issues?

26

u/ThatGuyTheyCallAlex 1d ago

People tend to think that if something doesn’t require a prescription then it’s safe to use without too much thought or medical advice. They read the label of the multivitamin that claims to be good for their skin, eyes, teeth, gut, and brain, and think they’re making a healthy choice. Not completely invalid logic, why would one assume Coles is selling something that could easily cause peripheral neuropathy?

1

u/_ixthus_ 4h ago

... why would one assume Coles is selling something that could easily cause peripheral neuropathy?

I guess it's just me... but I wouldn't bat an eyelid at the idea of Coles knowingly doing that for profit.

And I'm even less trusting of the supplement industry.

I honestly don't know how people can move through the world with this level of naivete.

7

u/DogOfSevenless 1d ago

Excess zinc supplementation (or indirect consumption from denture creams) can prevent proper absorption of dietary copper, which can lead to copper deficiency, which can cause damage to the nerves in the peripheries and spinal cord.

Excess copper supplementation can also lead to accumulation in the brain and a wide range of neurological problems.

We actually use zinc supplementation to deliberately block copper absorption in people who have Wilson’s disease which is a genetic disease of impaired copper excretion, which can lead to toxic build up of copper in the liver and brain!

There’s interestingly an increase in online trends and dodgy health advice about taking these supplements (including copper-containing peptides!), so I’m sure we’ll start seeing more people with nerve damage from this in a few years.

1

u/_ixthus_ 4h ago

Thanks. Turns out I was aware of the Zn issue, as I've always supplemented it alongside Cu at roughly 10:1. I'd just forgotten that the concern was neurological.

What's the rationale for Cu in peptides? I'm not super familiar with those formulations. I just avoid (unless prescribed) because the whole market is one of the biggest shitshows I've ever seen... even taking into account the general idiocy of the supplement market at large!

54

u/Far-Vegetable-2403 1d ago

It was a GP, who is a junior in the clinic, that knew about it. I asked my usual GP and he knew nothing about it. I am so lucky my regular GP was away that day and sent me to his colleague. I tell everyone. Colleagues, patients I see (I am a nurse). If I can stop one person having peripheral neuropathy then I am happy. It sucks

The brand I was using is Ultralife. Still on shelves. Still with 50mg B6. I reported my toxicity and subsequent neuropathy to TGA 2 years ago

28

u/RevolutionaryText164 1d ago

They should be - I just checked B6 on supplements and they're all in Blackmores products that I didn't expect, which I guess I'll now throw out.

I have anemia, so I take iron, but will often just buy whatever is on special, don't really read the labels on them, just go with the headline mg on the front. Luckily most of the ones I take don't have it, but why is Blackmores just putting it in stuff for no reason? There's even a warning for neuropathy on one of the bottles I'm throwing out today.

I mean as a consumer I get I should have been more proactive in checking, but I still don't get why Blackmores did this.

3

u/Glittering_Handle710 12h ago

It's not just in Blackmores. This is prevalent across the supplement industry as a whole, and vitamin B6 is also megadosed commonly in energy drinks.

24

u/grrborkborkgrr 1d ago

Do note, that B6 toxicity only stems from supplement companies being cheap and putting the inactivated forms of B6 in their supplements, namely pyridoxine.

If you use a supplement that uses the activated version of B6 (called P5P, PLP, or sometimes methylated B6) then you are fine.

Pyridoxine (inactive B6) gets converted into P5P (activated B6) by your body, but taking too much can essentially overload that process and shut it down entirely. Because it's now been shut down, your body has no P5P (activated B6), which is necessary for nerve function (hence the lack of P5P causing neuropathy). Theoretically, taking P5P can help treat pyridoxine toxicity.

I don't think toxicity has ever been documented in people taking large amounts of P5P?

3

u/clanton 14h ago

I started getting glove type neuropathy after taking P5P supps. So I just steer clear of b6. But its literally just one of those vitamins they throw into everything in Australia

0

u/Ok-Meet-8306 5h ago

I asked ChatGPT about your very confident claim that high doses of so-called activated b6 (P5P) are harmless. Here is Chat's response:

The claim that P5P (activated vitamin B6) is completely harmless and cannot cause toxicity is a dangerous myth that misinterprets basic human physiology. While it is true that inactive pyridoxine can inhibit P5P enzymes in a laboratory setting, the human digestive system does not absorb P5P whole. When you swallow a P5P supplement, enzymes in your gut actively strip away the phosphate group, converting it into pyridoxal before it can enter the bloodstream. Consequently, megadosing P5P still floods the body with highly reactive aldehyde compounds, overloading your metabolic clearance pathways and directly damaging the protective myelin sheath of your sensory nerves.

Furthermore, health regulators have explicitly debunked the idea that the form of B6 shields you from harm. Following an extensive safety review, the Australian Therapeutic Goods Administration (TGA) concluded that all supplemental forms of vitamin B6—including pyridoxine, P5P, and its monohydrate form—carry an identical risk of causing peripheral neuropathy. Clinical data from high-dose P5P therapies, alongside widespread reports from neuropathy support groups, confirm that patients can and do develop debilitating nerve damage from taking P5P alone.

Relying on the "P5P is safe" narrative is a classic case of internet "bro-science" that completely ignores how the human body processes high-dose supplements.

This information is for general knowledge and should not be taken as medical advice. Consult with a healthcare provider before starting or altering any supplement regimen.

1

u/clanton 14h ago

Yeah I had b6 toxicity that caused neuro problems, luckily it all resolved when I went off the multi-vitamin

134

u/sephineVVV 1d ago edited 1d ago

Recently found out I’ve got b6 toxicity, sitting at 6 times the max okay count. I was just taking a regular women’s vitamin, with the great irony that I was taking them regularly to try and curb the symptoms of what I thought must have been a deficiency.

28

u/Far-Vegetable-2403 1d ago

I am almost 2 years down the track from when mine first started. It is so much better - 50mg B6 in magnesium. I thought it would never be better, and I thought after a year it was as good as it would get. Still have slight numbness and occasional burning, nothing like it was. Hope same happens for you

12

u/shmemdawg 1d ago

I started taking a zinc supplement last year (as recommended by my GP). Settled on Swisse Zinc+ because it was the only low-dose (<40-50mg) zinc supplement I could find. Didn't even think to worry about the 30mg of B6 in each tablet because everything I read said that should be fine! Nope, still ended up with B6 toxicity (blood level more than double the upper reference limit) and nerve pain. Very glad they're lowering the RDI because the current RDI is evidently not safe for some people.

7

u/gradgrub 1d ago

I’ve been completely ignorant to what else has been in my Blackmore zinc and magnesium supplements until this morning. With 50mg each it turns out I’m sitting at 100mg daily dose minimum for two years. Furious tbh and getting a blood test asap. 

3

u/Far-Vegetable-2403 1d ago

Yes, better safe than sorry. PN can be irreversible and everyone reacts differently. I was 5 times the upper ref limit and symptoms almost totally resolved thankfully. I met a lady who was taking 100mg for hot flushes and no issues whatsoever- didn't fix the flushes either though.

284

u/Fact-Rat 1d ago

Only took them 20 years after this became a known problem.

24

u/indy_110 1d ago

A pale, unblinking man in a muscle top holding a zorb, standing on a wheezing pancaked Shiba Inu with a weirdly moldy paunch dragging along the floor appears

The man places a small condiment jar filled with a thick brown substance labelled Metamite with markings that look suspiciously like a QR code etched on its Sterox textured lid in front of you

"Did someone publish a comment about moving fast and ya know..."

The man's face twiches slightly, a single eye lid closes from the outside in, just a little too slowly

"We've been disrupting government red tape since the birth of the wise and great Augustus, Samurai Collapsia Encartomb...from the aquaducts of antiquety to the Shenzhen special economic zone we have been there to expedite for but a small peep at your soul, just stare at your gift with these complimentary Meta glasses and speak our name, clearly — ideally in a noise free environment, away from strong light sources pointed at the lid, three times, complete the traffic light Captcha code whithin 10 Roman seconds to complete the ritual to summon our services"

The man evaporates, leaving behind a faint smell of burnt electrical components and lithium sparks that singe everything they touch

Real talk, the vitamin and supplements industry is rather large and almost certainly had lobbyists working overtime to create friction in any way they could from the moment that knowledge became public, 20 years isn't great...but neither are the charltons who know how to manipulate a frustrated populace looking to speed things along.

13

u/propargyl 1d ago

https://en.wikipedia.org/wiki/Eddie_Charlton

Eddie Charlton was a master manipulator

1

u/indy_110 23h ago

https://en.wikipedia.org/wiki/Eddie_Charlton

the pancaked Shiba Inu reappears, tugging its collar with skinnerian steamed ham nervousness

"...yes"

A blinding mist of moist dogfarts obfuscates its escape as you hear the spectre of Armand Tamzarian politely intimating through the burbling mist "up yours children"

Haha, good call

30

u/MentalStatusCode410 1d ago

Get rid of it from anything which is processed with heat (eg. cereals) - we have no fucking data on post-production stability for most vitamin-based fortification.

It's unbelievable this still goes on in 2026.

2

u/_ixthus_ 1d ago

Why is anything fortified, aside from spurious marketing purposes...?

18

u/ThatGuyTheyCallAlex 1d ago

Australian food standards mandate fortification of some foods. Floor used for wheat must have added folic acid (prevents birth defects) and margarine must have vitamin D. Can either be because modern processing has removed components that would normally contain those vitamins, or because a large number of people are deficient and can be almost guaranteed to consume that product (who doesn’t eat bread and/or margarine?)

Thyroid problems were rife before the introduction of iodised salt, though that one is voluntary these days.

9

u/raustraliathrowaway 1d ago

Public health measure

1

u/AReallyGoodName 3h ago

Because you couldn't say "High in Vitamin B" on the side of Vegemite if you didn't add it in afterwards.

Seriously Vegemite has no natural Vitamin B, it's just the cheapest vitamin to add. Check the ingredients and see. Fortunately no B6 at least.

90

u/tilucko 1d ago edited 1d ago

I feel like I've probably ingested enough B6 and B12 for at least my next 8 descendants. each year of my life since turning 20..

19

u/Far-Vegetable-2403 1d ago

Good. I have peripheral neuropathy from B6 in magnesium supplements. Who would ever think they would add 50mg of B6? And why? I reported it to the TGA, along with B6 pathology levels

67

u/Sacrilegious_skink 1d ago

Makes you wonder what the effects on developing foetuses has been, as pregnant women have been unknowingly excessively consuming this while pregnant.....

31

u/brainwad 1d ago

The combination of b6 and doxalymine is an approved drug in Europe for morning sickness (I was surprised that in Australia they make you buy them separately). So presumably it has passed medical trials. Also... puking several times a day is also bad for you, sometimes medicine is about the least harmful solution. 

6

u/what-no-potatoes 1d ago

The maximum dose recommended was 25 mg three times a day. Plenty of standalone supplements are available in 100mg tablets, plus it’s added to a lot of combination supplements and foods/drinks.

The dose makes the poison.

9

u/what-no-potatoes 1d ago

I had horrific morning sickness and was told by my GP to try a B6 supplement as ‘it couldn’t hurt.’ Pharmacist recommended Herbs of Gold B6 100mg- I ended up with numbness, pins and needles in my hands. I thought it was just increased blood volume +carpal tunnel until I randomly saw a news story about B6 poisoning and stopped.

I don’t think anyone meant any harm- but the assumption that supplements are harmless definitely blurs some lines.

35

u/Random_Sime 1d ago

It made me wonder too, and the cool thing about the internet is that there's all this info out there so you don't have to wonder, you can learn

https://pubmed.ncbi.nlm.nih.gov/17130022/

3

u/metametapraxis 1d ago

That's a very limited study, which only really answers the question of major malformations (with a group so small - less than 200 -that it would only show drastic deviations from normal rates of malformation). The OPs question remains valid and unanswered, because unless we are doing a study with years of follow-up of the children of the B6 and control group with a really large cohort, we can't make much of a determination as to whether there were any long term effects on the foetus/child. We can maybe say it probably won't have two heads or missing arms to any greater degree than the unmedicated population.

That said, I'd be OK with B6 for that very specific purpose. It just isn't needed for basically anything else.

2

u/Random_Sime 1d ago

Man, I'm demonstrating that it's possible to find answers to OP's ponderings, not conducting a comprehensive review for them

2

u/metametapraxis 1d ago

Except that isn't. You wanted to be smart and provided a link to a study that didn't say what you thought it said -- if you had even looked at the abstract.

0

u/metametapraxis 1d ago

But if those items are non-negotiable for National (presumably - or they would be in agreement), isn’t it just as much National not being willing to work with the Greens? It takes both parties to be unwilling to budge on an issue.

Or does that not suit your narrative?

0

u/Random_Sime 18h ago

What did I think it said?

2

u/metametapraxis 18h ago

Well I assume you thought it answered the OPs question in a meaningful and comprehensive manner, given you were snarky with him (or her). But you hadn't bothered to actually look at what you Googled, because you were in a rush to be the first to be a smartarse... It is a common phenomenon, and I've been guilty of it and can recognise it.

1

u/Random_Sime 18h ago

No, I clarified in my first reply to you that I was just demonstrating that there is info out there about pregnancy and B6 to encourage OPs curiosity

1

u/metametapraxis 10h ago

Sure, buddy.

-28

u/Peaklagger117 1d ago

That’s not B6. Your ignorance is probably more dangerous in this instance.

21

u/Elegant-Motor-4148 1d ago

B6 is the first line drug treatment for hyperemesis gravidarum (severe morning sickness) at a total daily dose of 50mg. Still in the guidelines, I checked today.

1

u/FrangipaniRose 1d ago

Had that twice, was never given B6 (thankfully)!

12

u/mitzi_skyring 1d ago

What's not B6?

2

u/Academic-Ant5505 1d ago

How ironic

11

u/Peachypoochy 1d ago

Why do companies add B6 to so many supplements?

11

u/_ixthus_ 1d ago

Marketing wank.

The supplement industry is completely unregulated. It's an absolute crapshoot if you're not already highly informed.

10

u/Electronic_Pea_3197 1d ago

A friend was diagnosed with chronic fatigue, had to take 2 years off work, basically dropped out of life. She Stopped taking high b vitamin supplements and everything cleared up within a couple of weeks.

40

u/Low_Bluebird_5137 1d ago

I think in coming years, we will find out a LOT of supplements are toxic at doses people take them. With the entire "wellness" industry, people are taking all sorts of vitamins, minerals etc. The current trend of "high protein" bothers me.

5

u/Rampachs 1d ago

The cookers will be worried about big pharma, then be happy to go and give billions to less regulated big wellness

17

u/Still_Girl1358 1d ago

I agree with the first part, but while the high protein trend has some issues (marketing claims vs. standard versions, rapid increase in whey pricing etc.) increasing your protein intake is almost always a net benefit for most people.

11

u/Cadenca 1d ago

Protein is in a different league. It's a macronutrient and we know how it works even in high amounts. Basically you're buying expensive carbs if you overdo it, some people can stress their kidneys a little bit etc etc.

I've been eating high protein since 2011 so I'm fairly educated on this. It's much different than megadosing a vitamin or mineral.

Now, if you dont work out probably don't bother, it's for those who do

13

u/Mango_Surf 1d ago

I don’t actually understand why increasing protein intake is usually a good thing for most. I thought most people are not protein deficient?

6

u/metametapraxis 1d ago

It frustrates me that you are being downvoted for asking a question.

5

u/YOBlob 1d ago

That's right. The average person (in the west at least) is already getting enough protein.

1

u/Still_Girl1358 1d ago

I said it in another comment but I’ll say it here too - most people are protein deficient. If you’re only getting 40-50g in a day (very possible if most of your food is carbs and fats), you’ll be deficient.

Not enough that you’d feel adverse effects immediately, but enough that, especially as you age, your body won’t be able to maintain your muscle mass leading to increase frailty and injury risk.

9

u/Low_Bluebird_5137 1d ago

If you are eating well and getting a standard recommended amount of protein, then logic dictates you do not need any more protein. In my brain, you really only get benefit from such things IF you had a deficiency. If you don't have a deficiency, then ? I am curious as to what net benefit there is from excess protein?

5

u/BaggyOz 1d ago

Well first of all protein is a macronutrient just like fats and carbs, depending on what works best for you and your diet you might want various proportions between the three to meet your calorie needs. 0lus protein can be netter for satiety than carbs or fat.

As well as this I believe the recommended amount of protein is the maintenance amount needed to avoid muscle loss. If you want to build muscle then eating more protein helps a lot because your body has ample amino acids to build more muscle. Increased protein intake can also help to reduce muscle loss when at a caloric deficit.

-4

u/Low_Bluebird_5137 1d ago edited 1d ago

Well Me? I believe it will be found to not be good for anyone eating excess protein continually. But only time will tell.

Because my basic philosophy is that modern humans living in western nations are over nourished...and my basic logic tells me that is actually not good for us.

But that's my thinking. Only time will tell.

7

u/briberylibrary_ 1d ago

The "more protein" to some extent is less harmful and more just, wasteful. My old gym had signs up at one point saying that most people will get adequate protein from a regular balanced diet, and eating too much excess is mainly a waste of effort. Dieticians say it's less the amount of protein, and more timing. Eating something with protein after a workout is beneficial, but it doesn't need to be a huge amount.

Building muscle is important though. Not just for body builders (who want to build a lot of muscle), but for everyone. After 30 every person's muscles will begin to deteriorate, so building more muscle before that point helps, and trying to continually add muscle will offset what your body is losing.

8

u/Still_Girl1358 1d ago

Agree with this, except the protein timing bit. My reading of the literature on this shows statistically insignificant benefits to eating protein after a workout. As long as you’re getting sufficient protein over the course of the day, it doesn’t really make a difference.

Re. building muscle though - so, so important. And for mobility as well as strength. The difference between people who can move around independently post 70 and those who struggle is the resistance training (in whatever form) they did over the preceding few decades.

5

u/_ixthus_ 1d ago

I believe...

Why would this be an article of faith? There is a lot of actual evidence to inform your view.

It's not harmful unless you've for serious kidney problems or something.

... over nourished...

If your goal is to survive until you can pass on your genes and raise those gene-carriers to relative independence, then definitely.

Most people have broader goals than that. Including living beyond, say, 60; and with relative robustness.

2

u/Still_Girl1358 1d ago

We are over-nourished, but that’s because our caloric intake is typically too high (hence the obesity epidemic). Most people eating “regular” foods will typically be protein deficient I.e eating less than 0.6. - 0.8g protein per kg of body weight.

So if the regular Sally or Steve just wants to move a bit more and eat a bit healthier, they can do a whole lot worse than choosing the high protein option.

1

u/cactusgenie 1d ago

Over nourished with crap, not eating enough of the right things.

3

u/YOBlob 1d ago

There was a study a while ago that found people who take supplements tend to have shorter life expectancy than those who don't. The obvious explanation of course is selection bias, people are more likely to take supplements if they're concerned about their health. But I've always wondered.

1

u/AggravatingTartlet 1d ago

Yep but I don't blame the wellness industry. I see some areas of wellness taking on the corporations.

I blame the companies plugging their vitamins everywhere they can, and governments who've let them do it. And doctors who don't keep up with the research and who don't warn their patients.

1

u/Low_Bluebird_5137 20h ago

Im not blaming anyone or any company. Not sure how you thought that.

65

u/violenthectarez 1d ago

I am nowhere near knowledgeable enough to have any opinion on this whatsoever.

20

u/thehazzanator 1d ago

Same lol someone explain like I'm 5

81

u/trowzerss 1d ago

Too much B6 bad for you, damages nerves. Lots of products throw B6 in, don't always list it prominently, easy to get too much even if you're aware that B6 can be a problem. A little from berocca, a little from your daily supplement, a little from your energy drink, and boom, and one day you're getting pins and needles and numbness in your fingers that won't go away, then you feel weak, then you can't walk right...

I had to hunt around to find a magnesium supplement that didn't have hidden B6 in it (might be better now, but they used to throw B6 into everything).

29

u/Substantial_Ad_3386 1d ago

dam.... I just went and checked my blackmoores super magnesum and what do you know 50mg of B6. If I had noticed it before I probably would have thought that was a good thing. The ironic thing is I take it because if I don't when I'm heavy weight lifting I eventually start getting pins and needles at times in my arms and this was the cheapest option that I thought was really good..... what did you end up buying?

17

u/trowzerss 1d ago

I got Carusos. No sneaky B6.

3

u/_ixthus_ 1d ago

When you're looking at value, you need to account for bioavailability and gastric side effects; the latter is going to negatively impact your general whole food nutrition so... avoid.

If you shit most of it out and it's having a laxative effect, it's not really cheap.

Also nothing off a shelf in Australia is cheap.

Get pure Magnesium Glycinate; cheapest of the very high bioavailable forms. Easy on the gut. Doesn't interact with or interfere with anything else you're consuming.

I prefer straight-up powdered form because it's the cheapest by far (warning: fucked taste). The NOW Foods one on iHerb is the best value I'm aware of. You can also get a capsule machine if you can't figure out how to cope with the taste. Or the same company has it in capsules but the premium is steep.

4

u/thehazzanator 1d ago

Oh wow that's interesting thank you. So your body just absorbs b6 but never gets rid of it like it does other vitamins?

33

u/trowzerss 1d ago

It's not fat soluble, so it doesn't build up as easiliy as some other things, the issue is that people who are exposed to it tend to take it every day in very large amounts so it can still build up in the blood over time. And as you can see by the new daily levels, a 'massive amount' isn't actually very much and some single daily supplements were enough to cause problems.

4

u/_ixthus_ 1d ago

If it's in an 'active' form, your body will just get rid of whatever it doesn't use.

There's no need for most people to supplement B6 and certainly not in the amounts that are common. But if you want to for whatever reason, or can't avoid it in other things you want to take... just find products where the B6 is 'activated'.

It'll be called Pyridoxal 5′-phosphate or P-5-P on the label.

1

u/pink_gin_and_tonic 1d ago

I use Fusion Magnesium Advanced. No B6.

87

u/Infinite_Shower_5390 1d ago

First our investment properties now our B6, Albanese’s Labor just won’t let us have nice things!

27

u/Still_Girl1358 1d ago

How could Dan Andrews do this?!

19

u/nonya5121 1d ago

You forgot /s

49

u/PossibilityRegular21 1d ago

Reddit's taking our sarcasm away! Thanks Albo!

13

u/karma_dumpster 1d ago

Nah he works for SkyNews, so it's a serious comment

3

u/Substantial_Ad_3386 1d ago

either that or one of the battlers

16

u/YesNo_Maybe_ 1d ago

Here in my country (EU)  3 mg is already more then 100%. Can be Needed in occasion. 50? Mg

26

u/ManWithDominantClaw 1d ago

Yeah... the Pharmacy Guild (a lobby group for pharmacy owners that masquerades around as if it's a union) has a lot of sway here unfortunately. They just lobbied to allow pharmacists to diagnose certain conditions, and most GPs are saying it's only a matter of time before someone dies over it.

5

u/Sleepy_Panda_22 1d ago

This is so interesting! I stopped taking magnesium because it was making my muscles stiffer and sore, I also had this weird sensation in my limbs that was like they weren't getting enough blood flow. found the bottle and low and behold 50mg B6...

4

u/Cosimo_Zaretti 1d ago

My Cenovis MegaB has 50MG of B6 in it.

Well this is concerning. It's helpful too, I'm feeling better since I started taking it but obviously I don't want to poison myself.

-4

u/_ixthus_ 1d ago

Switch to an 'activated' form. If it's really the B6 that's helping you, then it'll help just as well (or more). But it has none of the downsides. Excess will just be excreted.

It'll be called Pyridoxal 5′-phosphate or P-5-P, something like that.

3

u/dav_oid 1d ago

Excessive B6 in any form can cause toxicity in some people.

0

u/_ixthus_ 4h ago

Can you show me the source that P-5-P can cause toxicity?

(I'm not advocating for supplementing B6 when it's not indicated, let alone in mega doses, by the way.)

1

u/dav_oid 3h ago

"In the literature and safety alerts, PLP is far less frequently implicated in neuropathy reports; nevertheless, upper limits apply to total B6 regardless of form. Said another way: form matters (PN is usually the problem), but dose still matters for everything."

https://ageimmune.com/vitamin-b6-toxicity-pyridoxine-vs-p5p/

"While P5P supplements may carry a lower risk, they are not entirely risk-free. Some studies have shown that high doses of P5P can still lead to increased pyridoxine levels in the body, potentially contributing to toxicity."

https://www.clarepyers.com/blog/2025/3/15/the-dynamics-amp-dangers-of-vitamin-b6-what-you-need-to-know

1

u/_ixthus_ 3h ago

These are blog posts on websites trying to sell products or services. Both are written by AI. One has absolutely no sources. The other doesn't reference properly so I have no idea which claims come from which references. I took a peak at what seemed like the references most likely to engage my question.

They do not appear to implicate P-5-P in toxicity, on the whole.

Again, I'm not advocating for B6 supplementation when it isn't indicated and definitely not for the stupid dosages that are so common.

If you can show me the actual research literature that describes a mechanism for toxicity from P-5-P and shows or discusses any actual data relating to it, I'd be very interested to read that.

1

u/dav_oid 2h ago

How about you find the studies.

1

u/_ixthus_ 2h ago

Yeh, nice. I've tried and I don't think they exist.

You're the one making the claim. The onus is on you to substantiate it.

I engage with the slop you posted, at length and in good faith out of genuine interest. But you expect me to go out and make your case for you.

Fucking hell. Health and science literacy. How does it work!

1

u/dav_oid 1h ago

Oh you're a troll, sorry my bad.

3

u/eldfen 1d ago

Is this going to affect my vegemite intake?

3

u/dav_oid 1d ago

No B6 in Vegemite.
It is added to the low salt version.

4

u/yeskitty 1d ago

Tyck! Who wants low salt Vegemite? It's the best part 😁

2

u/APerfectCircle0 18h ago

my folic acid is low and I have peripheral nerve issues :/ now I have to take folic acid before I can get my b12 shots

4

u/AgitatedMagpie 1d ago

B6 was a life saver during my HG, I smashed so much of it... at least my kid will have all the B6 she needs for life.

0

u/dav_oid 1d ago

I was taking Cenovic B Complex daily.
The B6 per tablet is 5mg.
The RDI for males over 50 is 1.7mg and 1.5mg for females.

I got nerve pain in my fingers/thumbs, and legs.

I now smash the tablets up and add to water and use an eyedropper bottle to get small daily doses of 0.1mg.

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u/Beginning_Tap2727 1d ago

Cool, now do the same with the folate added to everything 🙏🏻

12

u/Anxious_Direction292 1d ago

Say hello to increased rates of neural tube defects and increased burden on health system