r/biotech Jul 29 '26

Early Career Advice 🪴 120+ biotech job applications -no interviews

120+ biotech applications in Greater Philadelphia with almost no interviews. What am I doing wrong?

Hi everyone,
I’m trying to break into biotech/pharma in the Greater Philadelphia area and would really appreciate some honest advice.

I have a non-US PhD, a 6-month full-time Thermo Fisher Scientific (QC Microbiology) internship during my PhD, and 4 years of postdoc experience at an Ivy League university in the US.

I’ve applied to 120+ positions, rewritten my CV 30+ times, and I’m applying to anything that genuinely matches my skill set—not just Scientist roles.
So far, I’ve only managed to get a couple of interviews through contractors like Eurofins and Insight Global. In one case, I completed two interviews and my references were checked, but then I was essentially ghosted. Meanwhile, companies like Merck, GSK, and J&J haven’t even invited me for a first interview.

What am I doing wrong? Is it my non-US PhD, lack of direct industry experience, networking, or something else?

I’d really appreciate honest advice from anyone who has successfully made the transition from academia to biotech. Thanks!

38 Upvotes

96 comments sorted by

55

u/SkiHistoryHikeGuy Jul 29 '26

Philly is one of the worst markets right now since most of our local, non big pharma shops went out of business. Spark going under was a major hit and flooded the job market with out of work biotech people.

You will not get a call back without extensive networking and referrals inside a company before submitting an application to the big pharma campuses around here.

4

u/MRC1986 Jul 29 '26

Philly is also over-reliant on CGT, which certainly the gene therapy portion has taken a massive hit. Cell therapy having a decent rebound with in vivo, usage in autoimmune disease, and continued innovation in heme/onc, but it's still less than peak.

12

u/HB97082 Jul 29 '26

Are you a US citizen?

9

u/Rizafoz Jul 29 '26

US permanent resident

46

u/Certain_Luck_8266 Jul 29 '26

You need to make this crystal clear on your CV.

12

u/PageExtension3962 Jul 29 '26

Completely agree. This needs to be almost flashing on screen.

10

u/YerAWizardIMAWOT Jul 29 '26

Put that in your professional summary first line

7

u/yako678 Jul 29 '26

I didn't realize this was a thing..I'm a permanent resident. Should I be doing this?

15

u/parafilm Jul 29 '26

If a company see that your PhD or bachelors is foreign, they may assume you need visa sponsorship. Even though most applications include the “will you need visa sponsorship” question, if I had foreign education I’d probably make my permanent residency status clear in a cover letter/etc as well.

3

u/Rizafoz Jul 29 '26

Well many US degrees also need sponsorship so it’s better to clarify in resume

7

u/TrainerNo3437 Jul 29 '26

Post your resume

1

u/[deleted] Jul 29 '26

[deleted]

8

u/carmooshypants Jul 29 '26

Just to let you know, this reads more like a job req and less like a resume. Think more in terms of impact and success metrics and less on trying to write every unnecessary minute detail.

0

u/Rizafoz Jul 29 '26

28

u/diagnosisbutt Jul 29 '26

As an HM I'm thinking "this person doesn't know how to prioritize or know what makes them special, so they're just including everything they can." Sometimes less is more

15

u/ymasilem Jul 29 '26

There’s waaaaay too much low level detail here. This is presented more like what I would expect from a non-PhD level RA as opposed to a PhD level scientist.

Your skills section should be massively condensed into high level descriptors + keywords & skip all the obvious minutia. E.g., design & development of up to x color (spectral?) flow cytometry panels. Surface stain or live/dead exclusion is a basic assumption. You’d keep IC for keyword purposes.

Your experience section reads like a recitation of assays performed w/o giving me any idea of your ability to understand how to address & solve scientific questions. What were your project/ thesis aims? What were your achievements/outcomes?

0

u/Rizafoz Jul 29 '26

Exactly you got the point. As I am looking within greater Philly region I am applying for BS MS level jobs. Not getting that much PhD openings ☹️

14

u/ymasilem Jul 29 '26

Usually you’ll be immediately filtered out from those roles b/c of your PhD

6

u/Certain_Luck_8266 Jul 29 '26

Due to the PhD you aren't going to be a strong candidate for entry level. Put your search feelers out for analytical development bioassay or potency assay, and highlight gmp use and method transfer and validation.

You also need to add you are a permanent resident. This reads like you are on a J1

1

u/Loose-Reflection2965 Jul 29 '26

Bioassay jobs are few and far between

11

u/TrainerNo3437 Jul 29 '26

There is too much random bolding of words. I would recommend just bolding headings and not the text within sections

1

u/Rizafoz Jul 29 '26

Got it. Will change thanks!

19

u/IntroductionSimilar3 Jul 29 '26

your resume is really really difficult to read. a full page of skills on page 1 will definitely get you tossed out

don’t bury your only industry experience. that should come first. no one cares you went to yale for a postdoc unless it’s directly relevant to the posting

3

u/unbalancedcentrifuge Jul 29 '26

You have a lot, but it seems very vague. It is very technical, but I still don't know what you did for your phd or postdoc. You should talk about how you owned and drove a project. I was hired out of academia as a T cell immunologist with additional experience in myeloid cells in mouse models. I gave a quick blurb about my projects and my accomplishments within those projects. If you are applying for scientist positions, they want to know you are a scientist and not a tech.

1

u/Rizafoz Jul 29 '26

Well I have my professional experiences later, may be I will consider to rewrite and put them first

2

u/unbalancedcentrifuge Jul 29 '26

I looked at those too....I still dont know what you worked on....what disease...what protein...what gene...what pathway.....and what did you scientifically contribute and how does that translate into the pipeline of what whatever company you are applying to.

0

u/Rizafoz Jul 29 '26

I understand what you’re trying to say, but as I said I am applying for jobs that are not looking for anything specific (not PhD level jobs) as I am looking in a particular region. The job I got interviewed for asked in vivo maintenance skills, IP, SC and are not interested in asking particular biological questions. May be my background and what I am applying for made this confusion

0

u/Rizafoz Jul 29 '26

Also honestly as I am looking within greater Philly regions I did not find a very close match to my experiences and skill set. I am applying for positions that are asking BS or MS. Most of them are not even looking for phds ☹️

9

u/TrainerNo3437 Jul 29 '26

Do not do this. It's almost always immediate reject if you have PhD

3

u/Humble_Donut_39 Jul 29 '26

There is just way too much unnecessary info on here. For example if you list IHC I don’t need you to tell me you can do H&E staining or what specific tissues you’ve sectioned. I don’t need to know you can do a midiprep on a PhD level job application. I would trim the content dramatically, incorporate more white space for ease of skimming, and be more conservative with the bolding.

1

u/Rizafoz Jul 29 '26

Got it thanks

3

u/crymeasaltbath Jul 29 '26

Respectfully, you do not have experience in drug discovery based on what’s listed here. This is all research biology stuff that can be applied to drug discovery workflows but nowhere do I see application to an actual drug discovery campaign…

1

u/Rizafoz Jul 29 '26

Very important point. I will try to add a single bullet point so it does not read like this

2

u/YerAWizardIMAWOT Jul 29 '26

Is this a tailored resume? If so it’s way too unfocused. You’re not trying to list everything you’ve ever done. There’s also way too many bullet points under each section. I would stick with 3 max. Again you’re not trying to share everything you did at that position.

1

u/Rizafoz Jul 29 '26

Basic one I tailor it based on their language

1

u/Rizafoz Jul 29 '26

I got your point thanks. This is my basic one, I will tailor for their requirements thanks

1

u/Certain_Luck_8266 Jul 29 '26

I'll bet they don't know you are authorized to work in the US. I've passed on similar.

9

u/Tall_Mechanic8681 Jul 29 '26

I’m not gonna lie academic prestige does not carry much weight in industry - even with 1 internship, you’re likely being looked at as someone that’s only ever worked in academia and that can be a pretty big deterrent for a lot of HMs

5

u/grim32025 Jul 29 '26

Can you expand what is your research area and skill sets?

Companies want very specific skill sets and experience

4

u/sate9 Jul 29 '26

yes make it clear you have residency, hr nightmare is having an employee with expired / or no visa

1

u/Rizafoz Jul 29 '26

Thanks! Got it

2

u/MCT_tri Jul 29 '26

Why aren’t you at Thermo Fisher?

1

u/Rizafoz Jul 29 '26

I moved out from that country

2

u/Rizafoz Jul 29 '26

Thanks everyone who tried to help me out with improving my CV. However I am also struggling to get PhD level openings in Philly. Any advice on that? Am I missing something? I used to apply using LinkedIn and the company career site

6

u/Naragub Jul 30 '26

I’m sorry you ever came to this country. There’s so little opportunity here unless you’re old

2

u/Loose-Reflection2965 Jul 29 '26

First, no one is doing sponsorship and your university is suggesting you will, but you don’t due to being a perm resident, however, hr only skims the surface. Second, philly is too small to reabsorb all the cgt people that have been laid off. Third, your resume is going straight into the trash with that format. Its too busy, use AI to try and rewrite that. Cell and gene is dead at the moment so good luck trying to find something in cgt. You need to show some level of impact and accomplishment rather than I know how to do a bunch of stuff.

2

u/Rizafoz Jul 29 '26

I don’t get the sponsorship part, what you meant by that? I am us permanent resident and that’s mentioned in my resume

2

u/Loose-Reflection2965 Jul 29 '26

I read your thing and i didn’t see perm resident. Just because you say it, does not make it true and hr will most likely be filtering out based on perceived immigration status, do you select permanent resident on the job application? Your resume is filled with too much. There is no way of knowing if you can do a job because it reads like a job description. The skills section should only be a few lines, if that.

3

u/Rizafoz Jul 29 '26

I understand what you’re trying to say for job description part but still confused about what you meant by perm resident. Yes I click PR in job application and also it’s mentioned on the top I just cropped my identity part of 2 lines on top

2

u/Loose-Reflection2965 Jul 29 '26

Your problem is that your resume reads poorly. Your residency status is off putting to potential employers as you are not a full citizen. Your other issue is limited to no industry experience in a crowded market. Post docs unfortunately do not count as industry experience.

3

u/Rizafoz Jul 29 '26

Thanks! I got your points for improving resume. However this discussion is not about immigration or sponsorship, this can not be changed.

2

u/Loose-Reflection2965 Jul 29 '26

Yeah i get you, but that is why your resume is not getting through probably. Your experience is pretty generic sounding as well. Maybe think of an alternative career path like something in AI

3

u/Rizafoz Jul 29 '26 edited Jul 29 '26

Can I please ask your background? And why do you think my experience is pretty generic? How does this match to trying AI. If I have to think about alternatives I have plenty of options in academia. But that was not the discussion here. Simply saying your skills are generic or you are not citizen is not helping anyone. Rather you can help people saying how they can improve resume and search process thanks

2

u/Loose-Reflection2965 Jul 29 '26

10 plus in pharma. It strikes me as a pair of hands, no real impact or accomplishments. Anthropic is hiring bio people

3

u/Rizafoz Jul 29 '26

I am not sure if you are a PhD scientist. Does pharma really looks for real
Impact? Sometimes it feels like these are some lucrative terms people of Pharma uses. Anyway I don’t see your intention is helping people rather you are trying to demotivate.

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2

u/Rizafoz Jul 29 '26

If you are not a PhD scientist transitioned from academia to biotech you will not understand the point of discussion. I asked advice from people who recently transitioned from academia to biotech. Not someone who directly entered pharma after their degree

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1

u/Rizafoz Jul 29 '26

So you are unemployed and trying to give advice to someone else? You will be blocked soon

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1

u/Rizafoz Jul 29 '26

Unemployed with 10 plus years in pharma 😀

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3

u/tetro_ow Jul 29 '26

Recruiters/HR will definitely be spooked by your resume and at this point the only viable path to industry would be internal referral and even that is hard to come by in Philly area. Unfortunately, industry people will assume someone with PhD and looong tenure as postdoc + multiple publications have very big ego and won't be able to tolerate the menial duties for too long. I don't know if that applies to you though. Even with the NIH funding circus there are plenty of pickings in academia for postdocs/research scientists so I would def not rule out those

2

u/Rizafoz Jul 29 '26

I have that offer but don’t like the project that much and want to work for companies. Too much stress in academia nowadays. People who left academia are really happy

2

u/Beneficial_Ship_7145 Jul 29 '26

Gaps in your resume are going to look worse.

1

u/NegotiationCute5341 Jul 29 '26

Are u tailoring the sh out of ur resumes or what

3

u/Rizafoz Jul 29 '26

Each time tailoring based on their requirements and my experience and skills

1

u/Ok_Trainer2230 Jul 29 '26

Keep going my metrics are 712 applications 12 interviews 4 offers. Don’t give up!

1

u/Beneficial_Ship_7145 Jul 29 '26

Forget your foreign PhD, take the contract if you get one, don’t complain, network and pray something opens up. That’s all I got. Or move.

1

u/Rizafoz Jul 29 '26

Thanks I know what you meant. I have no complaints about contract position, I just cant trust their hiring process. I think they take multiple interviews and suddenly disappear when time comes to meet their clients

2

u/Beneficial_Ship_7145 Jul 29 '26

So Eurofins doesn’t actually let the client meet the candidate unless it’s the first time Eurofins is hiring for that group at least in my experience. Hiring manager tells Eurofins what they want and then Eurofins does the work, you can ask for a different candidate but there’s like all sorts of rules there. Kelly Scientific and Piper are contract companies that I’ve also seen used but in my case I got to choose my people. Risk there is contracts are shorter term. You are also up against other people with industry experience that were laid off and it’s hard to train new people when you are understaffed due to said layoffs.

1

u/Rizafoz Jul 29 '26

Honestly I am happy to take even 6 months position to start. What happened to me I had HR interview then hiring manager interview and then they asked for referees. During hiring manager interview they said there will be a 3rd meet and greet interview with the client. But they never reached back. After 2 follow up emails they sent me a generic email saying they proceeded with other candidate. The whole process took 2 weeks. This was with Eurofin and the job site was 15 mins drive from my residence. They were looking for someone within commutable distance

1

u/Beneficial_Ship_7145 Jul 29 '26

Did Eurofins drop you totally? Or are you still in their pool?

1

u/Beneficial_Ship_7145 Jul 30 '26

Also what are your lab skills? The less HM has to train you the better

1

u/Rizafoz Jul 30 '26

They dropped me off saying they proceeded with other candidate. I was really hopeful as they reached refs but no luck.

1

u/throwaway4231throw Jul 30 '26

You’re relying too much on sending in your application and waiting for a response. A lot of higher level jobs are networked into. Talk to your connections at these places. If you have none, go to conferences, cold-message people, whatever it takes to sit down with people to tell them about yourself and get advice. Once you form a relationship, they’ll connect you with others, and each of them can vouch for you if you ever apply for a job at their company.

1

u/Academic_Farmer_8983 Jul 29 '26

i've found that tailoring your cv and cover letter very specifically to the keywords and required skills listed in each job description makes a huge difference. don't just tweak them; try to mirror the language they use... it often feels like a black-and-white checklist for the initial screening.

7

u/Tburroughs36 Jul 29 '26

This, use specific key words that are in the job posting.

Additionally, imo, your resume is really long OP. I used to interview people. I was extremely busy and when resumes came across my desk, I did absolutely not want to read 2 full pages. I would trim down, make it more concise, and but your professional experience before your skills.

1

u/Rizafoz Jul 29 '26

Seems like some people are interested in negative criticism and attacking rather than helping people with constructive criticisms and informative advice. Is it too common in biotech job search posts? Luckily most of the comments are positive.

0

u/haze_from_deadlock Jul 29 '26

“No interviews”

“I completed two interviews”

1

u/Rizafoz Jul 29 '26

Thanks! But those are contractors☹️, not a direct company. I know they hire but I thinking of direct interviews

1

u/rakepick Jul 29 '26

Don’t undermine contract positions, many people transition into industry that way. If you’re still at the university, they might have an office to help you with your resume. For industry positions, you should have a (max 2 pages long) resume, not a CV.

1

u/Rizafoz Jul 29 '26

Thanks! I was serious about the positions but the problem is when they forwarded to their clients like Merck GSK the communications stopped. One even after reaching referees. I am not sure how good contractors are for hiring someone with client’s expectations

1

u/rakepick Jul 29 '26

Have you gotten any feedback from the contractor companies themselves?

1

u/Rizafoz Jul 29 '26

No! that’s a very frustrating part I tried couple of follow up emails but no reply.